Milad Yousefi

Computational Biology & Bioinformatics

A passionate researcher at the intersection of mathematics, artificial intelligence, and biological sciences with a strong foundation in Applied Mathematics and expertise in computational approaches to solve complex biological problems.

Location: Tabriz, Iran
Profiles: Google Scholar | ORCID

Academic Background & Expertise

About Me

I am a computational biology researcher with a foundation in Applied Mathematics from Tabriz University. My work bridges the gap between mathematical modeling, computational methods, and biological applications, with a particular emphasis on neuroscience and medical informatics.

My interdisciplinary approach combines:

  • Mathematical Modeling: Developing fuzzy models and computational frameworks for biological systems
  • AI Applications: Applying machine learning and deep learning to biological and medical data
  • Computational Neuroscience: Modeling neuronal dynamics with a focus on LIF (Leaky Integrate-and-Fire) neuron models
  • Bioinformatics: Analyzing genetic and biological data using computational methods

Educational Background

Bachelor of Science in Applied Mathematics
Tabriz University, Iran (2019-2023)
GPA: 17.43/20 (3.58/4.00)
Thesis: "An Investigation into Fuzzy Modeling Techniques for Input Current Conversion in LIF Neuron Models"

My thesis work focused on developing innovative fuzzy logic approaches to model the complex non-linear relationship between input currents and neuronal responses in LIF neuron models, which are fundamental to computational neuroscience.

Research Focus Areas

Computational Biology Research

My research spans several interdisciplinary areas within computational biology, with a primary focus on applying mathematical models and computational methods to understand biological systems and improve healthcare outcomes.

Computational Neuroscience

  • Neuron Modeling: Developed fuzzy modeling techniques for input current conversion in LIF neuron models, creating more biologically accurate computational representations
  • Alzheimer's Detection: Explored AI-based approaches for early diagnosis of Alzheimer's disease using retinal imaging biomarkers
  • Signal Processing: Applied advanced signal processing techniques to neurological data to extract meaningful patterns and biomarkers
  • Neural Networks: Implemented artificial neural networks that mimic biological neural network properties for medical applications

Bioinformatics & Systems Biology

  • Genetic Analysis: Conducted HLA distribution analysis of Azeri and Kurd ethnic groups, providing insights into population genetics and potential disease associations
  • Systems Biology: Analyzed biological pathway data to understand systemic responses to treatments and disease states
  • Biological Data Processing: Developed specialized algorithms for processing high-dimensional biological datasets
  • Statistical Genomics: Applied statistical methods to analyze genomic data, identifying significant patterns and correlations

Healthcare AI Applications

  • Brain Stroke Prediction: Developed machine learning models to predict stroke likelihood using multiple risk factors and biomarkers
  • Cancer Imaging Analysis: Created lung cancer segmentation and classification tools using CT scan images and deep learning
  • Treatment Efficacy Analysis: Conducted statistical comparison of Gabapentin and Cinnarizine for tinnitus treatment in patients with sensorineural hearing loss
  • Medical Image Processing: Applied image compression and feature extraction techniques using SVD for diagnostic applications

Research Publications

Selected Publications

My research has resulted in several publications and ongoing research projects in peer-reviewed journals, focusing on the application of computational methods in biological and medical contexts:

Artificial Intelligence for Multiple Sclerosis Management Using Retinal Images: Pearl, Peaks, and Pitfalls

This paper examines the potential of AI-based retinal imaging analysis for Multiple Sclerosis management, discussing both opportunities and challenges in this emerging field.

Co-authors: Chee Peng Lim, Shadi Farabi Published

Retinal imaging and Alzheimer's disease: an artificial intelligence-based future

This research explores how AI can leverage retinal imaging biomarkers for early detection and monitoring of Alzheimer's disease, presenting a future direction for non-invasive diagnostics.

Co-authors: Hamidreza Ashayeri, Ali Jafarizadeh, Fereshteh Farhadi, Alireza Javadzadeh Published

Advancements in Radiomics and Artificial Intelligence for Thyroid Cancer Diagnosis

This paper reviews and analyzes recent developments in radiomics and AI applications for improving thyroid cancer diagnosis accuracy, discussing the integration of computational approaches with clinical practice.

Co-authors: Shadi Farabi Maleki, Ali Jafarizadeh, Mahya Ahmadpour Youshanlui, et al. Submitted

HLA distribution of Azeri and Kurd ethnic groups: 6 years investigation of Northwest Iran

This study presents a comprehensive analysis of HLA distribution patterns among Azeri and Kurd populations in Northwest Iran, providing valuable data for immunogenetics, transplantation medicine, and population genetics.

Co-authors: Sima Shahmohammadi-Farid, Shadi Farabi, Leyla Mandalo Submitted

An Investigation into Fuzzy Modeling Techniques for Input Current Conversion in LIF Neuron Models

This ongoing research explores novel fuzzy logic approaches to more accurately model the non-linear relationships in neuronal responses, enhancing the biological realism of computational neuroscience models.

Co-authors: Fariba Bahrami, Shadi Farabi Ongoing Research

Technical Expertise

Skills & Competencies

My interdisciplinary research requires proficiency in various technical skills across mathematics, programming, and data analysis:

Programming & Development

  • Languages: Python, C++, R, PHP
  • Frameworks: TensorFlow, Django, Laravel
  • Software Engineering: Design patterns, architecture
  • Data Processing: NumPy, Pandas, SciPy

Mathematics & Statistics

  • Linear Algebra: Matrix operations, SVD
  • Statistical Analysis: Hypothesis testing, regression
  • Fuzzy Mathematics: Fuzzy logic, fuzzy sets
  • Optimization: Linear and non-linear methods

AI & Machine Learning

  • Deep Learning: Neural networks, CNN, RNN
  • Machine Learning: Classification, regression, clustering
  • Computer Vision: Medical image analysis
  • Feature Engineering: Preprocessing, selection

Bioinformatics & Computational Biology

  • Sequence Analysis: DNA/RNA/protein sequences
  • Biological Models: Neuron models, pathways
  • Medical Informatics: Health data analysis
  • Biostatistics: Specialized statistical methods

Professional Development

I continually enhance my skills through specialized online courses and self-directed learning:

  • Advanced Bioinformatics: Specialized course covering genomic data analysis, sequence alignment, and structural bioinformatics
  • Computational Neuroscience: Focused study of neural modeling, neural data analysis, and dynamical systems
  • Deep Learning Specialization: Completed all 5 courses by Andrew Ng, covering neural networks, CNN, RNN, and optimization techniques
  • Machine Learning: Comprehensive training in supervised and unsupervised learning methods, model evaluation, and practical applications

Academic & Research Experience

Professional Experience

Teaching Assistant - Linear Optimization

Department of Mathematics and Computer Science, Tabriz University

  • Conducted weekly problem-solving sessions for undergraduate students
  • Prepared and administered midterm and final exams
  • Provided personalized guidance on optimization techniques and applications
  • Instructor: Dr. Vakili

Teaching Assistant - Combinatorics

Department of Mathematics and Computer Science, Tabriz University

  • Led weekly sessions explaining complex combinatorial concepts
  • Graded student assignments and provided constructive feedback
  • Developed supplementary learning materials for challenging topics
  • Instructor: Dr. Behmaram

Teaching Assistant - Differential Equations

Department of Mathematics and Computer Science, Tabriz University

  • Facilitated weekly sessions focusing on problem-solving and theory applications
  • Designed and supervised class projects connecting differential equations to real-world problems
  • Provided individualized support to students struggling with complex concepts
  • Instructor: Dr. Bahrami

Research Internship - Center of Immunology

Tabriz Medical Science University

  • Assisted with immunological data analysis using statistical methods
  • Participated in research projects involving HLA typing and distribution
  • Applied computational techniques to analyze immunogenetic patterns
  • Collaborated with medical researchers on interdisciplinary projects

Major Research Projects

  • Brain Stroke Prediction using ML & DL: Developed predictive models incorporating multiple risk factors and biomarkers to assess stroke likelihood, achieving high accuracy in early detection
  • Lung Cancer Segmentation & Classification: Created automated tools using convolutional neural networks to process CT scan images, aiding in precise cancer detection and characterization
  • Tinnitus Treatment Analysis: Conducted statistical comparison of Gabapentin and Cinnarizine efficacy in patients with sensorineural hearing loss, providing evidence-based treatment recommendations
  • Image Compression and Face Recognition: Applied singular value decomposition (SVD) for efficient image compression and feature extraction in facial recognition systems
  • Hotel Booking Demand Analysis: Performed comprehensive statistical analysis of hotel booking datasets to identify patterns and factors influencing cancellations and demand fluctuations

Future Research Directions

Research Vision

Building on my foundation in computational biology and bioinformatics, I aim to pursue several innovative research directions that leverage interdisciplinary approaches:

Integrating AI with Neurological Biomarkers

My ongoing work with retinal imaging and Alzheimer's detection has highlighted the significant potential of using non-invasive biomarkers for neurological disease detection. I plan to expand this research to other neurological conditions, developing more sensitive computational models that can identify subtle changes in various biomarkers.

Advanced Computational Models for Neurological Systems

Building on my work with LIF neuron models, I intend to develop more sophisticated computational frameworks that can better simulate complex neuronal networks and interactions. These models could provide deeper insights into neural functioning and potential therapeutic targets for neurological disorders.

Personalized Medicine through Computational Biology

By combining genetic data, computational models, and machine learning, I aim to contribute to the field of personalized medicine by developing tools that can predict individual responses to treatments based on biological markers and patient characteristics.

Cross-disciplinary Collaboration

I'm particularly interested in forming collaborations across mathematics, computer science, medicine, and biology to tackle complex healthcare challenges that require multidisciplinary approaches. These collaborations could lead to novel computational methods with real-world clinical applications.

Educational Initiatives

Drawing from my experience as a teaching assistant, I'm passionate about developing educational resources that make computational biology more accessible to students from diverse backgrounds, particularly focusing on practical applications and hands-on learning experiences.

Contact & Connect

Get in Touch

I welcome collaboration opportunities, research discussions, and connections with fellow researchers in computational biology, bioinformatics, and related fields.

Contact Information

Email: miladdyousefi@gmail.com | yousefimiladdd@gmail.com

Location: Tabriz, Iran

Academic Profiles

Google Scholar: Milad Yousefi

ORCID: 0009-0006-5790-5144

Collaboration Areas

I'm particularly interested in collaborating on projects related to:

  • Computational approaches to neurodegenerative disease detection and monitoring
  • Advanced mathematical modeling of biological systems
  • AI applications in medical imaging and diagnostics
  • Interdisciplinary research bridging mathematics, biology, and computer science
  • Educational initiatives in computational biology and bioinformatics